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This is an incidental pharmacological effect rather than its intended mechanism of action
It is a cornerstone in the treatment of type 2 diabetes mellitus because of its capacity for glycemic control and lower risk of hypoglycemia when compared to other anti-diabetic medications
Clinical trials for semaglutide began in the early 2010s, with the SUSTAIN phase 3 trial program enrolling patients starting in 2012
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The largest increases in T2D diagnosis were observed in Class 3 obesity, while sleep apnea diagnosis rates saw the largest proportional growth in Class 1 obesity
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