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Bass says
In a 16-week randomized study of 30 obese men with functional hypogonadism who had responded poorly to lifestyle measures, liraglutide raised total testosterone by an average of 2.6 nmol/L and significantly increased LH and FSH a pattern suggesting the HPT axis itself recovered rather than testosterone simply being replaced (Jensterle et al., 2019, Endocrine Connections )
Stress and Hormone Modulation: Evidence suggests DSIP may regulate cortisol, growth hormone, and other neuroendocrine pathways, contributing to stress reduction and recovery
Others say it burns the skin and it is not worth in terms of results, pain and budget
The Long R3 designation describes two structural changes
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