A fraction of that, sometimes one-tenth, targeted at the inflammatory machinery that drives autoimmune disease from the inside out
Classical pro-inflammatory cytokines (IL1B, IL6, TNF) and pattern recognition receptors (TLR2, TLR4) are markedly increased, along with adhesion molecules (VCAM1, ICAM1) and chemokines (CCL2, CXCL8) that promote leukocyte recruitment and vascular injury (Falco-Holanda et al., 2021
If berberine is included in the formulation (as the marketing language suggests, but the ingredient list does not confirm), it would represent an ingredient with more metabolic research, though primarily studied by oral administration rather than transdermal delivery
Frequently Asked Questions What are Peptide Stacks
Full per-study counts, arm-level percentages, and system distributions are provided in S1