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Sabbagh M, Boschini C, Cohen S, Fugger M, Jessen F, Martino GG, et al
The FDA has documented cysts, knots, and permanent scarring in recipients of unapproved fat-dissolving injections
However, orforglipron: Provides double-digit weight loss Works without needles or refrigeration May improve long-term adherence compared with weekly injections This places it among the most promising oral GLP-1 options currently in late-stage development
Trends Endocrinol Metabol: TEM (2016) 27(6):42738
The data comes from separate trials with different populations, so direct comparison has limitations
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