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Tissue-specific peptide processing occurs through prohormone convertases that produce glucagon in the pancreas and GLP-1 and GLP-2 in the intestine 2
Excretion Pathways Elimination occurs through both renal and hepatic routes: Primary urinary excretion accounting for approximately 53% of administered dose for GLP1 Fecal elimination contributing approximately 19% of dose excretion Minimal intact peptide in urine (approximately 3.1% for GLP1
Too many companies and clinicians are not paying attention to what specifically is being lost
The drug keeps you ahead of that signal for a while, but weight loss plateaus within about a year
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