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Endothelial cells promote stem-like phenotype of glioma cells through activating the Hedgehog pathway
Phase II neutralizes them by covalently attaching a conjugation group (glucuronic acid, glutathione, sulfate, acetyl, methyl, or amino acid) that increases polarity, reduces reactivity, and enables transport into bile or urine
Glutathione injections, like infusions, involve administering glutathione directly into the bloodstream
Reported side effects are generally mild, including bloating, gas, and digestive discomfort, particularly when first starting the supplement
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