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That absence of data is not the same as a clean bill of health, and it's the reason a personal or family history of hormone-sensitive cancer (breast, prostate, colorectal) is one of the clearest contraindications for this compound rather than a discussion topic
Are side effects manageable, or should you reduce
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9 Nrf2 is usually locked in the cytoplasm, but activation by DMF/MMF allows it to translocate to the nucleus where it activates a pathway of genes involved in antioxidant responses, detoxification, and the activity of cytoprotective anti-inflammatory factors
References Drucker, D
