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Studies document enhanced angiogenesis with increased blood vessel formation in wound beds, providing better oxygen and nutrient delivery to healing tissues
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Diverse immune-related gene families involved in pattern recognition receptors (PRRs) (e.g., peptidoglycan recognition proteins (PGRP), scavenger receptor (SCR), and galectins (GALE)), signal modulation and amplification (e.g., clip domain serine proteases (CLIP) and serpins (SRPN)), signal transduction pathways (e.g., TOLL), and other effector systems (e.g., caspases (CASP)) also exhibited significant downregulation
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