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Structure of Escherichia coli Grx2 in complex with glutathione: a dual-function hybrid [PMID: 25004967] Laboratory literature summary: Structure of Escherichia coli Grx2 in complex with glutathione: a dual-function hybrid of glutaredoxin and glutathione S-transferase

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CB-1158 could block myeloid cell-mediated inhibition of T cell proliferation, increase the number of tumor-infiltrating CD8 + T cells and NK cells, and increase the expression of inflammatory factors and interferon-, thereby changing the immune microenvironment to promote inflammation and reduce tumor immune escape, inhibiting tumor cell proliferation