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Specifically, the cut-off distance is 4.0 for salt bridge analysis [50], while the hydrogen bond analysis employed two criteria: (a) a cutoff value of the angle formed by acceptor (A), donor (D) and hydrogen (H) ( ADH ) of 30

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This dual action helps regulate blood glucose levels without causing significant hypoglycemia when used as monotherapy (though risk increases when combined with insulin or sulfonylureas)

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