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Topiramate is another medication that supports weight reduction by influencing cravings, meal pacing, and satiety pathways
Discovery of gastric inhibitory polypeptide and its subsequent fate: personal reflections
Caloric intake can also drop low enough to cause malnutrition
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Given the high prevalence of psychiatric comorbidities, undertaking randomized controlled trials in patients with primary polydipsia is difficult and is also mirrored by the lack of research in this field (5)
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