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As explained by Kanner et al (1979), reserpine's high lipid solubility can cause it to accumulate in lipid bilayers, which can result in a more long-lasting effect when its effects are studied in cell preparations containing lipid membranes

Mice were housed with no more than five animals per cage and were kept on an ad libitum diet

Exenatide once weekly over 2 years as a potential disease-modifying treatment for Parkinson's disease: protocol for a multicentre, randomised, double blind, parallel group, placebo controlled, phase 3 trial: The 'Exenatide-PD3' study

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PMID 27265421