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In another study, HTY demonstrated hippocampal neurogenesis when administered orally and it activated neurogenesis in the dentate gyrus of normal adult mice, aged wild-type mice, and Btg1-knockout mice modeling accelerated neural aging, HTY-induced neuroprotection involved reduction of oxidative stress markers and apoptotic neuronal death, suppression of microglial activation and pro-inflammatory cytokine release, and functional integration of newly generated neurons into hippocampal memory circuits

Baer DJ, Stote KS, Paul DR, Harris GK, Rumpler WV, Clevidence BA

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Both p53 TAD PEP and CAND showed limited efficacy in inducing cell death in both dividing and senescent cells (Figure

Antioxidants: Vitamin C, Vitamin E, Coenzyme Q10, N-acetylcysteine Micronutrients: Zinc ranges from 15 to 30 milligrams per day, selenium ranges from 55 to 200 micrograms per day, and folate is 400 micrograms per day