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In this common form of the disease, the "heart pumps normally but is too stiff to fill properly, rendering the heart unable to support the body's need for oxygen-rich blood," according to a meeting news release

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This result led to FDA approval of Wegovy for an additional cardiovascular indication in March 2024

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LC also plays an important role in the regulation of metabolic pathways involved in skeletal muscle protein balance: proteolysis and protein synthesis [3]