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"Safe, gradual weight loss should take priority over aggressive reduction." Lee Kyung-ju, professor of gastroenterology at Hallym University Dongtan Sacred Heart Hospital, said: "If upper abdominal pain or discomfort recurs during rapid dieting, an abdominal ultrasound to check for gallstones is important." Lee added: "Even during obesity treatment, avoiding excessive short-term weight loss or very-low-calorie diets and consulting with medical professionals to establish a gradual reduction plan benefits gallbladder health."

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High dietary fat consumption impairs axonal mitochondrial function in vivo

There is no clinical-trial program combining cagrilintide with retatrutide, and no data on such a pairing

Dutta, A., Abmayr, S