TBARS assays were performed in hippocampal homogenates from control (n = 5), IH 10 (Saline IH , n = 5), and IH 10 with concurrent administration of the superoxide anion scavenger, MnTMPYP, (MnTMPyP IH , n = 5)
Obsessive-compulsive disorder (OCD): An RCT in 48 patients found that NAC (2,400 mg/day) as an add-on to fluvoxamine significantly improved Yale-Brown OCD Scale scores compared to placebo over 12 weeks (Afshar et al., J Clin Psychopharmacol, 2012) [72]
Injections are more effective than oral supplements due to higher bioavailability
In vitro and preclinical literature may discuss cell proliferation, pathway models, or experimental endpoints, but those findings should stay tied to the model being studied
855, no