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Hypoxic lung cancer-secreted Exosomal miR-23a increased angiogenesis and vascular permeability by targeting Prolyl hydroxylase and tight junction protein ZO-1

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Preclinical studies have explored GHK-Cu effects in cardiovascular applications, where the peptide demonstrates capacity to reduce atherosclerotic plaque formation in hyperlipidemic mice through anti-inflammatory effects and improved endothelial function

These ailments encompass a spectrum ranging from chronic ocular surface diseases that profoundly impair quality of life, such as dry eye, conjunctivitis, pterygium, and blepharitis, to progressive, sight-threatening pathologies including cataracts, glaucoma, corneal opacity, and refractive errors that can culminate in permanent vision loss [1]