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Figure 1 shows the most relevant aspects of the benefits/risks profile of GLP-1 RAs
L., Cornett, E
Therefore, reduced food intake primarily drives weight loss secondary to GLP1RA
Relevant studies have found that patients with colorectal cancer commonly exhibit dysbiosis in their gut microbiotas, with significant differences in the composition and relative abundance of microbial communities compared to healthy individuals [110]
Worse than lifestyle alone When directly compared, weight regain after stopping drugs was significantly faster than after stopping behavioural programmes, independent of how much weight was initially lost
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