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Because semaglutide is more potent and stays in the system for a full week, rushing to the maintenance dose would overwhelm the gastrointestinal system
The largest of these (still fairly small, n=159) was a randomized and controlled clinical trial published in the New England Journal of Medicine , and found that a dose of 100 mcg twice per day improved quality of life, reduced eye involvement, and slowed disease progression among participants with mild Graves' orbitopathy (compared to pentoxifylline or placebo)
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Dont try to use partial doses from a nearly empty pen combined with partial doses from a new pen
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