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Semaglutide, also referred to by the brand name Ozempic, helps mimic the GLP-1 hormone

3 The findings were significant: Semaglutide improved both cognitive and motor function in mice with MS-like disease Reduced demyelination (the nerve damage that characterises MS) Promoted remyelination (nerve repair) Reduced neuroinflammation by lowering inflammatory markers Protected against oxidative stress damage This was the first study to examine semaglutide specifically in an MS model, and the results suggest that the medication may have direct neuroprotective effects beyond its weight-loss benefits

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These observations receive support of our mutagenesis studies by measuring both cAMP responses and receptor binding affinities (Fig

De Luca, C