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doi: 10.1186/s12967-020-02356-2 22 CorbittMEaton-FitchNStainesDCabanasHMarshall-GradisnikS

No, decreased libido is not commonly listed as a direct side effect of semaglutide

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A large 2026 study of people who discontinued a GLP-1 medication found that just 14% adopted structured lifestyle changes

Evaluation typically includes BMI measurement, screening for contraindications like personal or family history of medullary thyroid carcinoma, and baseline metabolic labs