Structure Of Melanotan 2 10MG IUPAC Name: (3S,6S,9R,12S,15S,23S)-15-[[(2S)-2-acetamidohexanoyl]amino]-9-benzyl-6-[3-(diaminomethyli deneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-2,5,8,11,14,17-hexao xo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide

CV standard-of-care treatments at baseline included 1,2 : Medication Class Lipid-lowering therapy Platelet aggregation inhibitors Angiotensin-converting enzyme inhibitors or angiotensin II receptor blockers Beta-blockers Percentage of Patients (N=17,604) 90% 86% 74% 70% Throughout the trial, CV therapies could be adjusted at investigator discretion according to current standard of care 1 Baseline cardiometabolic parameters 1 Heart rate A1c Systolic blood pressure Diastolic blood pressure Triglycerides Total cholesterol LDL cholesterol HDL cholesterol Wegovy injection (n=8,803) 69 bpm 5.8% 131 mm Hg 79 mm Hg 138.6 mg/dL 155.5 mg/dL 78.5 mg/dL 44.1 mg/dL Placebo (n=8,801) 69 bpm 5.8% 131 mm Hg 79 mm Hg 139.5 mg/dL 156 mg/dL 78.5 mg/dL 44.2 mg/dL *Standard of care included CV risk-factor management and individualized healthy lifestyle counseling (including diet and physical activity)
Borum PR
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