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Published online May 31, 2018
However, a recent meta-analysis of 14 randomized, placebo-controlled trials in 2,149 participants with heart failure found that supplemental coenzyme Q 10 (30-300 mg/day) resulted in a 39% reduction in mortality (seven studies), improved exercise capacity (four studies), but had no effect on left ventricular ejection fraction (nine studies) compared to placebo (34)
The label lists dose, form (oral, liposomal, or IV), and frequency, all of which help the clinician assess any theoretical risk
Strategies to minimize symptoms include slower titration schedules, maintaining adequate hydration, and consuming smaller, more frequent meals
L-Carnitine is essential for transporting long-chain fatty acids into mitochondria for conversion into usable energy
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