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Controlled trials reveal that chronic citrulline supplementation lowers peripheral and central systolic pressures, diminishes arterial stiffness indices, and improves skeletal- muscle perfusion during exercise rehabilitation
You can see a full list here , but in our experience, the most common complaints include: Nausea, occasionally leading to periods of vomiting Diarrhea and/or constipation Fatigue Bloating/gas Because these medications require titration (i.e
Kitakata H, Endo J, Matsushima H, Yamamoto S, Ikura H, Hirai A, et al
This supplement may cause gastrointestinal discomfort in some individuals
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