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Following this, Western Blot analysis was used.In HCT116 cells, Fer-1 pretreatment (1M) was observed to reverse the HT-induced up-regulation of Tfr1 expression and down-regulation of SLC7A11 and GPX4 protein expression levels (Fig

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The prevalence of vitamin B12 deficiency is particularly elevated among patients with T2D, with studies demonstrating that up to 64% of those with DPN exhibit altered (low or borderline) vitamin B12 levels compared with only 17% of patients without neuropathy

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We then asked whether normalizing the DA level would improve the energy metabolism deficit