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5-AMINO-1MQ Description: 5-Amino-1MQ (5-amino-1-methylquinolinium iodide) is a small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT)
PGP is a stabilising motif derived from biological observation: it resists most endopeptidases and aminopeptidases thanks to rigid prolines (pyrrolidine cycle)
The Pro-Gly-Pro C-terminal extension provides partial protection against proteolysis but does not prevent systemic clearance
Then, they get weekly injections until they start to get better
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