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After the development of GLP-1 receptor agonists demonstrated the utility of targeting incretin biology, researchers expanded into dual agonist strategies
MusettiACattivelliRGuerriniAMirtoAMRiboniFVVaralloGet al
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The ongoing PreVitaCOV Phase III trial (NCT05638633) at Wrzburg University Hospital in Germany is actively evaluating the efficacy of high-dose neurotropic B-vitamins (including 50 mg of active B6) in treating the extreme fatigue, dyspnea, and cognitive deficits of Post-COVID Syndrome
First-generation agents looked riskier in the raw numbers, but dose was the stronger signal after adjustment
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