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Estimation of folate levels were done under long term MTX treatment (2 nM and 10 nM, 3 days) where the macroscopic phenotypic traits were striking

To test if MS4A15 extensively inhibits ferroptosis, we generated pooled Ms4a15 -overexpressing mouse immortalized fibroblasts ( Ms4a15 OE) [32, 33] and characterized resistance to different ferroptosis inducers (1S,3R)-RSL3 (RSL3), imidazole ketone erastin (IKE), ferroptosis inducer derived from CIL56 (FIN56), and genetic ablation of Gpx4 (Fig

Hypoxia-induced SHMT2 protein lactylation facilitates glycolysis and stemness of esophageal cancer cells

Sophisticated Analytical Instrumentation Facility (SAIF-CIL), Panjab University, Chandigarh for the sample characterization

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