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Compared with the Control group, there were 721 DEGs in the Model group, including 170 upregulated genes and 551 downregulated genes

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The altered gut microbiome in Alzheimers disease can contribute to the development and progression of the disease through several interconnected mechanisms: Firstly, the dysbiotic microbiome can lead to increased intestinal permeability, allowing the translocation of bacterial metabolites, toxins, and inflammatory molecules into the systemic circulation