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This can contribute to endothelial dysfunction, making arteries less responsive and creating conditions that favor inflammation and plaque formation

Energy expenditure declines

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Patients need a meaningful time investment from their care team to drive big-picture changes leading to better GI health

Patients with severe gastrointestinal motility disorders (such as gastroparesis), history of bowel obstruction, or significant abdominal surgical history should discuss their potential increased risk with their provider before starting weight loss injections