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A 2024 systematic review cataloged the preclinical BPC-157 literature and identified a consistent pattern: strong effect sizes in rodent models across multiple injury types, with no dose-limiting toxicity observed at standard experimental doses [10]

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More recently, tirzepatide a synthetic 39-amino-acid peptide that dual-agonizes GLP-1 and GIP receptors was approved as Mounjaro (diabetes, 2022) and Zepbound (obesity, 2023)