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The therapeutic modalities used to treat GBMs are surgery, chemotherapy, especially temozolomide, radiotherapy, targeted therapy (bevacizumab), immunotherapy, vaccine therapy, virotherapy, and focused ultrasound therapy [58, 59]
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Circ Res 93:354363 Shi F, Wang YC, Zhao TZ, Zhang S, Du TY, Yang CB, Li YH, Sun XQ (2012) Effects of simulated microgravity on human umbilical vein endothelial cell angiogenesis and role of the PI3K-Akt-eNOS signal pathway