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Mice lacking dopamine (DA) D1 receptors (Rs) displayed increased Gln levels in the brain, an effect ameliorated by L-DOPA administration 28
In one case report, early antenatal exposure to GLP-1 therapy was associated with neonatal macrosomia, shoulder dystocia and neonatal hypoglycemia
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This extends review timelines by 36 weeks on average compared to KPV protocols, which can reference published Phase 2 trial data and established adverse event profiles
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