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It transforms retatrutide from a powerful appetite suppressant into a metabolic reshaping tool

Avoid certain foods with iron-rich meals: Tea, coffee, and foods high in calcium can reduce iron absorption

Side effects: LaValle says that with daily pills, the body experiences a different exposure pattern than with weekly injections, which may lead to varying patterns of nausea or GI upset

Managing side effects: Nausea or digestive issues can often be eased with meal adjustments, hydration, or slower dose increases

By 2024, the associated weight loss was only half as large as the 2021 estimate, and the effect on A1C was not statistically different from zero