Helmstdter J, Frenis K, Filippou K, Grill A, Dib M, Kalinovic S, Pawelke F, Kus K, Krller-Schn S, Oelze M
Due to the increasing popularity of GLP-1RAs in patients with obesity, it seems crucial to recognise the peri-operative management in this group of patients
However, clinical studies have shown that many patients on semaglutide GLP-1 experience a significant weight reduction, with some patients reporting a loss of about 5-10% of their initial body weight in the first month of treatment
Kang, Z
Whilst glucagon typically raises blood glucose, early Phase 2 trial data suggest that, when combined with GLP-1 receptor activation, its net effect may include increased calorie burning and a potential reduction in liver fat, without causing clinically significant rises in blood sugar