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Ubiquitin ligases: structure, function, and regulation
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31 We found a noticeable upregulation of genes encoding transporters of specific amino acids (Supplementary Table 1), especially those genes encoding a glutamine transporter and a glutamine-binding protein, which were significantly upregulated in comparison to other specific amino acid transporters
The authors described these structural models as the basis for rational development of p53 inhibitors targeting the senescent cell biology field and diseases linked to cellular senescence including cancer
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