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Indeed, glutamine-derived R-2-HG accumulates and prevents the differentiation of myeloblasts, resulting in uncontrolled growth of blood cells 122
Stouffer JL, Tyler RS
MCM, methylmalonyl CoA mutase [1,5]
Some risk factors for vitamin B12 deficiency include: Old age Atrophic gastritis (a condition that damages the stomach lining) Certain health conditions and medications A vegan or vegetarian diet How Do I Know If My Vitamin B12 Levels Are Low
These include: The severity of B12 deficiency The presence of underlying health conditions Genetic variations affecting B12 metabolism The duration of supplementation Knowing these factors helps tailor the dose to meet individual needs, ensuring the best results
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