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Anabolic Signaling: The released GH stimulates the liver to produce IGF-1, which activates the mTORC1 pathway in muscle (protein synthesis) and the Runx2 pathway in bone (osteoblast differentiation)
The Oxford Centre for Evidence-Based Medicine 2011 Levels of Evidence 17 was used to grade the quality of evidence (OCEBM)
L-carnitine also may help reduce lactic acid accumulation and support a higher lactate threshold, but most importantly, it may help reduce mental fatigue
As these were already lower in the mutants compared to the WT this led to stronger phenotypes regarding root length and total biomass production
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