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Tirzepatide potently activates the GLP-1R signalling pathway to stimulate glucose-dependent insulin secretion through activity at the GIP receptor (GIPR) or the GLP-1R
Aim for a weight loss rate of 0.5 to 1 kg per week , which is less likely to trigger gallstone complications
Nguyen T, Wen S, Gong M, et al
It is approved for treating hyperglycemia in patients with T2DM in many countries (105, 106)
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