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In 1993, the World Health Organization (WHO) divided laryngeal neuroendocrine neoplasms into carcinoid, atypical carcinoid, and small cell carcinoma (1)

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However, a subsequent single oral gavage experiment did not result in detectable bacteria in the blood or organs, thus proving that direct oral-gut translocation is not a pathway for systemic spread of P.g , although other studies using repeated oral inoculations reported P.g colonization in distant organs ( 3 The effect of oral pathogens on intestinal microbiota and its role in systemic diseases Microbial translocation studies reveal unique oral-gut axis dynamics