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GLP-1 agonists mimic the effects of this hormone, making them an effective treatment for diabetes and obesity

Given research suggests these drugs are more effective when combined with physical activity and dietary changes, current FDA labeling recommends they be prescribed concurrently with a behavioral and lifestyle treatment plan, Meister explained

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Activation of monocytes, DCs, and macrophages drives the release of key cytokines, including IL-1, IL-6, TNF-, IL-17, and IL-23, which together establish a core inflammatory network that sustains disease development and progression [274]

158 By far the majority of mutations (85 percent) are missense mutations causing the substitution of a single amino acid