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Data availability Cryo-EM maps have been deposited in the Electron Microscopy Data Bank ( with the accession numbers of EMD-65817 for wtVLP, EMD-65818 for sVLP, and EMD-65819 for sVLP-3G10

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Kallianpur AR, Hall LD, Yadav M, et al

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Our Epithalon lots are produced under strict process control with 99% purity by HPLC

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Lyophilised: -20C long-term

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As a reduction of 0.5% in HbA1c is a clinically important difference (Zinman et al., 2018), a greater reduction by liraglutide may contribute to the renoprotective effects

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