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5.2 Regulation of macrophage phenotypes by helminths prevents the development of T1D and T2D The possibility that macrophages mediate the beneficial effect of helminths in diabetes emerged from experimental studies using mouse models in which the depletion of T-cells, or the genetic ablation of T-cell signaling molecules, failed to impact the protection from disease elicited by infection with Litomosoides sigmodontis, Heligmosomoides polygyrus , or Schistosoma mansoni (98, 99)
(PubMed) The same review warns that systemic administration (IV) may shift melanin production, altering skins natural photoprotection and potentially increasing the risk of UV-induced skin damage or cancer a risk especially relevant in sunny climates
Brain Behav Immun 50:101114
Use the listed once-weekly protocol as part of your structured wellness plan, and follow clinic guidance before adjusting your routine
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