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Rodent Thyroid Differences : Rats and mice have a higher number of GLP-1 receptors on their thyroid C-cells compared to humans, making their thyroids more sensitive to the hormone

PMID: 29437021 DOI: 10.2174/1871530318666180213110815

If your body is operating under higher physiological load and getting less parasympathetic recovery overnight, lower spontaneous activity is a plausible downstream effect rather than just appetite or motivation changes

Given that the Wegovy injection received a restricted NICE recommendation in 2023, limiting NHS prescribing to specialist weight management services, oral semaglutide (the pill) is likely to follow a similar path

A company spokesperson told Reuters that Hims has not compromised on safety or efficacy and uses a liposomebased technology intended to support absorption