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The most common side effects are nausea, reduced appetite, constipation and fatigue, usually around dose increases
This may be too dilute for typical protocols
This reduction in MDSC-driven immunosuppression could promote a more pro-inflammatory environment, allowing CAR-NK cells to more effectively target and kill tumor cells
References Askarpour, M., Hadi, A., Miraghajani, M., Symonds, M., Sheikhi, A., & Ghaedi, E
Two-layer sustained-release microneedles encapsulating exenatide for type 2 diabetes treatment
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