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Combining GLP-1 medications with resistance training at least twice weekly, adequate protein intake (1.2-1.6 g/kg body weight daily), 150-300 minutes of moderate-intensity aerobic activity weekly, and prioritizing 7-9 hours of quality sleep significantly enhances abdominal fat reduction and preserves lean muscle mass
Storage: Keep the medication refrigerated and shield it from light
FPG and fasting insulin and fasting triglyceride could not be included in the analyses involving HOMA and TyG, respectively, due to multicollinearity
Semaglutide and Tirzepatide help reduce systemic inflammation, which can ease joint pain, support thyroid function, and even improve mood and energy
Importantly, GLP-1 appears to attenuate reward-driven food consumption by modulating dopaminergic signaling in the mesolimbic system, potentially reducing preference for high-fat, energy-dense foods [36]
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