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Figure 1 The pooled effect of the four trials comparing GLP-1 receptor agonists with metformin showed a large and significant decrease in C-reactive protein (SMD 0.95
Dietitians are experts in managing gastrointestinal symptoms
"We speculate that semaglutide shows an anti-inflammatory effect by promoting the transformation of microglia from M1 to M2 type in the brain of 3xTg mice, and thus exerts a neuroprotective effect," write the researchers
Doctors often start with a lower dose of both medications to reduce the risk of side effects
But the therapeutic compounds are compromised
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