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This individualized approach to dosing (with maintenance doses of 5 mg, 10 mg, or 15 mg based on response and tolerability) can help optimize both efficacy and tolerability

Strain-specific brain metallothionein II (MT-II) gene expression, its ethanol [PMID: 12658104] Laboratory literature summary: Strain-specific brain metallothionein II (MT-II) gene expression, its ethanol responsiveness, and association with ethanol preference in

Oxidative Medicine and Cellular Longevity , 2012, 324832