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Different isomer ratios matter and may alter metabolic effects

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In the context of skin melanocytes, particularly cannabidiol (CBD) and cannabigerol (CBG) exert significant modulatory effects on the cellular redox state, primarily through antioxidant, receptor-mediated, and lipid-regulating mechanisms, which may influence melanoma development and oxidative stress mitigation 162,163,164

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They are just at different points on a trajectory of progression where the body may no longer be able to compensate as well and require drugs (prediabetes vs