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10.1124/jpet.121.001152 21

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The diagnostic process typically begins with clinical suspicion, often based on a rapidly enlarging, painful mass

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Aspirin may retain a role in select inflammatory or hereditary risk settings, while GLP-1 agents could become foundational for metabolically driven risk reduction

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Although individual-to-individual variability was high, Gene Set Enrichment Analysis (GSEA) using the KEGG pathway database revealed that MOTS-c regulated processes related to (i) metabolism, including those known to be regulated by MOTS-c ( e.g

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The New England Journal of Medicine , 10.1056/NEJMoa2511774

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